饮酒与男性血清TG、HDL-C以及TG/HDL-C比值的关系

目的 探讨饮酒与男性血清甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）以及TG/HDL-C比值的关系。方法 利用2010~2012年中国居民营养与健康状况监测在广西的监测数据，以年龄18~65岁之间的男性为研究对象，共1290人纳入研究，数据录入采用中国居民营养与健康状况调查数据录入系统进行，应用SPSS19.0比较不同酒精摄入量男性基本信息分布、血脂 (TG、HDL-C、TG/HDL-C) 水平、异常率比较；采用非条件logistic回归分析不同酒精摄入量男性血脂异常患病危险的OR值。结果 极重度饮酒男性的TG水平和TG/HDL-C比值均明显高于不饮酒者（P<0.05)；重度饮酒者HDL-C明显高于不饮酒者和轻度饮酒者（P<0.001)。男性居民TG、HDL-C、TG/HDL-C异常率分别为37.4%、22.6%和29.1%。不同酒精摄入量分组间TG异常率和TG/HDL-C比值异常率不同（P均<0.01)，TG异常率和TG/HDL-C比值异常率均随着酒精摄入量的增加而升高。调整了年龄、BMI、中心性肥胖等影响因素后，当男性居民的酒精摄入>48.0g/ d时，患高TG血症和TG/HDL-C比值异常的OR（95%CI）分别为2.24(1.49~3.37)和1.62(1.03~2.56)。结论 饮酒与升高男性高TG血症发病危险相关，当酒精摄入量>48.0g/d时增加男性高TG血症和TG/HDL-C比值异常的发病危险。

The Relationship between Alcohol Intake and TG,HDL-C Levels and TG/HDL-C Ratio in Men

Objective To explore the association between different alcohol intake and the level of triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and TG/HDL-C ratio in men. Method The data were collected from Investigation of the China Nutrition and Health Survey (2010~2012). 1290 men aged from 18 to 65 years were selected in the study. Date input by the Entry System of Chinese Nutrition and Health survey. Data analysis was conducted by SPSS 19.0. Basic information, lipid (TG、HDL-C、TG/HDL-C) levels and abnormal rate in men with different alcohol intake groups were compared. Logistic analysis was used to analyze the OR (95% CI) value of dyslipidemia in men with different alcohol consumption. Results The TG level and TG/HDL-C in men with extremely heavy drinking was significantly high than non-drinking（P < 0.05). And the level of HDL-C in heavy drinking men was higher than non-drinking and light drinking men with significant difference (P < 0.001). The abnormality rate of TG and TG/HDL-C all increased with the increased alcohol intake (P < 0.01) The abnormal proportion of TG, HDL-C and TG/HDL-C were 37.4%、22.6% and 29.1%, respectively. After adjustment of age, BMI, center obesity and other factors, the OR (95% CI) for anomalies risk of TG and TG/HDL-C in men with alcohol intake >48.0 g/d were 2.24 (1.49~3.37) and 1.62(1.03~2.56), respectively. Conclusion Alcohol intake was positively associated with high TG. The abnormal risk of TG and TG/HDL-C in men with alcohol intake > 48g/d increased.