| VEGFR-3 mRNA在乳腺癌中的表达及临床意义 |
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| 引用本文： | 王虎霞,王光辉,朱 江,宋张骏,韩丕华,杨晓民,邓智平,盛 薇.VEGFR-3 mRNA在乳腺癌中的表达及临床意义[J].现代肿瘤医学,2016,0(6):902-905. |
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| 作者姓名： | 王虎霞 王光辉 朱 江 宋张骏 韩丕华 杨晓民 邓智平 盛 薇 |
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| 作者单位： | 1.陕西省肿瘤医院乳腺中心，陕西 西安 710061;2.西安交通大学医学院第一附属医院普外科，陕西 西安 710061 |
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| 摘 要： |
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| 关 键 词： | 乳腺癌 VEGFR-3 mRNA 淋巴结转移 |
Expression and clinical significance of VEGFR-3 mRNA in breast cancer |
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| Wang Huxia,Wang Guanghui,Zhu Jiang,Song Zhangjun,Han Pihua,Yang Xiaomin,Deng Zhiping,Sheng Wei.Expression and clinical significance of VEGFR-3 mRNA in breast cancer[J].Journal of Modern Oncology,2016,0(6):902-905. |
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| Authors: | Wang Huxia Wang Guanghui Zhu Jiang Song Zhangjun Han Pihua Yang Xiaomin Deng Zhiping Sheng Wei |
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| Institution: | 1.Breast Disease Center,Tumor Hospital of Shaanxi Province,Shaanxi Xi'an 710061,China;2.Department of General Surgery,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China. |
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| Abstract: | Objective:To study the expression and clinical significance of VEGFR-3 mRNA in breast cancer.Methods:RT-PCR was adopted in detecting the VEGFR-3 mRNA expressions in 60 cases of breast cancer.Take 15 cases of breast fibroadenoma as control.Results:The positive ratio and degree of VEGFR-3 mRNA in breast cancer was higher than the control group.VEGFR-3 mRNA was conspicuously higher in lymph-node-positive group than in lymph-node-negative group.The expression of VEGFR-3 mRNA was positively correlated with axillary lymph node metastasis.There were no statistically significant differences in pathologic features,tumor size and clinical stage.Conclusion:The expression of VEGFR-3 mRNA was higher in breast cancer,and it played an important role in the lymph node metastasis. |
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| Keywords: | breast cancer VEGFR-3 mRNA lymphatic metastasis |
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