膜荚黄芪中黄酮类化学成分研究

目的 : 研究膜荚黄芪中黄酮类化学成分。方法: 采用硅胶柱色谱和HPLC制备色谱方法分离纯化得到单体化合物，采用有机波谱方法鉴定化合物结构。结果: 从膜荚黄芪乙醇提取物中分离得到8个黄酮类化合物，分别为2’,7-二羟基-3’,4’-二甲氧基异黄烷-2’-O-β-D-吡喃葡萄糖苷(1)，3’,4’-二甲基异黄烷(2)，芒柄花素(3)，芒柄花素-7-O-β-D-葡萄糖苷(4)，毛蕊异黄酮(5)，(6aR,11aR)3-羟基-9,10-二甲氧基紫檀烷(6)，(6aR,11aR)9,10-二甲氧基紫檀烷-3-O-β-D-葡萄糖苷(7)，7,2’-二羟基-3’,4’-二甲氧基异黄烷-7-O-β-D-葡萄糖苷(8)。结论: 化合物1为首次从该属植物中分离得到。

Studies on flavonoids and related constituents from Astragalus membranceus(Fisch) Bge

Objective: To study flavonoids and relatedconstituents from Astragalus membranceus(Fisch) Bge. Methods: Chemical constituents were isolated and purified by repeated column chromatography (silica geland preparative HPLC). Their structures were elucidated by spectral data analysis. Results: Eight compounds (1-8) were isolated and their structures were identified by comparing their spectral data with literature values as follows: sphaerophyside SB(1), isomucronulatol(2), formononetin(3),formononetin-7-O-β-D-glycoside(4), calycosin(5), methylnissolin(6), (6aR,11aR) 9,10-dimethoxypterocarpan-3-O-β-D- glycoside(7), 7,2’-dihydroxy-3’,4’-dimethoxy-isoflavane-7-O-β-D-glycoside(8). Conclusion: Compounds 1 could be isolated from this plant for the first time.