Free radical oxidation and antioxidant activity in blood plasma and myocardium during long-term dipyridamole treatment |
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| Authors: | Ivasenko I N Shlyakhto E V |
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| Affiliation: | (1) Laboratory of Hematology, Institute of Cardiovascular Diseases, I. P. Pavlov State Medical University, St. Petersburg |
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| Abstract: | Activation of free radical oxidation and inhibition of antioxidant activity in mouse myocardium after long-term dipyridamole treatment were demonstrated using chemiluminescent techniques. At the same time, dipyridamole 10-fold inhibited free radical oxidation and slightly increased antioxidant activity in the plasma. Dipyridamole-induced platelet disaggregation was accompanied by an increase in platelet count. |
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| Keywords: | myocardium plasma platelets free radical oxidation antioxidant activity |
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