动态血压监测对防治靶器官损害应用价值的研究

目的以动态血压监测为研究手段，探讨动态脉压变化与高血压靶器官损害之间的相互关系，为临床预防、逆转和保护高血压靶器官损害提供科学依据。方法采用无创性携带式袖带法动态血压监测仪对高血压病人进行昼夜血压波动情况的监测，同时利用彩色多普勒超声诊断仪观察高血压对靶器官（心脏）损害的渐进情况。结果随着年龄增长，脉压呈显著性增加趋势，脉压升高是LVMI的重要决定因素，而动态血压可客观准确地监测动态脉压波动。从而有效防治靶器官损害。结论动态脉压是高血压病人心血管事件的独立预测因子，动态血压监测更能反映高血压靶器声损害程度。

Value of dynamic monitoring of blood pressure in prevention of target organ damage

Objective To investigate the relationship between ambulatory pulse pressure and target organ damage in senile essential hypertension. Methods Blood pressure fluntuations of hypertension patients were monitored day and night by using portable non-invasive ambulatory blood pressure cuff method,while the color Doppler ultrasound diagnostic observation of hypertension on target organ （heart） damage was also made. Results With aging,the pulse pressure showed markedly increasing tendency,that was an important determinant of LVMI,yet ambulatory blood pressure could monitor the pulse pressure fluctuations objectively and accurately,so as to control the target organ damage effectively. Conclusion Ambulatory pulse pressure in hypertension patients with cardiovascular events is an independent predictor. And ambulatory blood pressure monitoring can reflect the extent of hypertensive target organ damage.