| 灯盏花素对肾缺血再灌注损伤中线粒体的保护作用研究 |
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| 引用本文： | 石少慧,王怀颖,靳袆,辛海涛. 灯盏花素对肾缺血再灌注损伤中线粒体的保护作用研究[J]. 河北职工医学院学报, 2006, 23(1): 4-5 |
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| 作者姓名： | 石少慧 王怀颖 靳袆 辛海涛 |
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| 作者单位： | 河北省职工医学院,生化教研室,河北,保定,071000 |
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| 摘 要： | 目的观察肾缺血再灌注对线粒体的损伤及灯盏花素的保护作用.方法采用大鼠肾缺血再灌注模型,观察灯盏花素对缺血再灌注肾组织线粒体中 SOD、 GSH- PX活力及 MDA含量的影响.结果灯盏花素用药组线粒体中 SOD、 GSH- PX活力显著高于缺血再灌注组, MDA含量显著低于缺血再灌注组(P<0.01).结论灯盏花素在肾缺血再灌注中对线粒体的损伤有明显保护作用.
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| 关 键 词： | 灯盏花素 肾脏 缺血再灌注损伤 线粒体 |
| 文章编号： | 1008-6692(2006)01-0004-02 |
| 收稿时间： | 2004-12-01 |
| 修稿时间： | 2004-12-01 |
Protective effccts of Erigcron Breviscapus on renal mitochondria from ischemia reperfusion in rats |
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| Shi Shaohui, Wang Huaiying ,Jin Yi et al.. Protective effccts of Erigcron Breviscapus on renal mitochondria from ischemia reperfusion in rats[J]. Journal of Hebei Medical College for Continuing Education, 2006, 23(1): 4-5 |
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| Authors: | Shi Shaohui Wang Huaiying Jin Yi et al. |
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| Affiliation: | Department of Biochemistry, Hebei Medical College for Continuing Education, Baoding 071000 |
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| Abstract: | Objective To study the protective effects of erigeron breviscapus on renal mitochondrias from ischemia reperfusion injury in rats.Methods The activities of SOD,GSH-PX catalase and MDA in preparations of renal mitochondrias were respectiveiy measured.Results The activities of catalase,GSH-PX.total SOD of mitochondria were significantly enhanced in the erigeron breviscapus group,compared with lschemia reperfusion group(P<0.01).MDA concentration was significantly decreased(P<0.01).Conclusion The results showed that erigeron breviscapus can significantly protect renal mitochondria from ischemia repeffosion in rats. |
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| Keywords: | Erigeron Breviscapus kidney ischemia - reperfusion injury mitochondria |
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