M-VAC versus CisCA--chemotherapy in the treatment of advanced bladder cancer. |
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| Authors: | D Heimbach M Wirth H Frohmüller |
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| Affiliation: | Department of Urology, University of Würzburg Medical School, FRG. |
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| Abstract: | The results of this study do not demonstrate a superiority of M-VAC chemotherapy over a modified CisCA regimen chemotherapy. M-VAC, however, proved less toxic than CisCA in terms of side effects. Neither CisCA nor M-VAC was effective as a curative treatment for patients with distant metastases. A durable complete remission of 22.5 months was seen in only 2 of the 12 patients with locally advanced tumors without distant metastases treated with M-VAC, and one of 35 months was observed in only 1 of the 6 cases with locally advanced tumors treated with CisCA chemotherapy. |
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