The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo |
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| Authors: | Way Sing Sing Wilson Christopher B |
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| Affiliation: | Department of Pediatrics, University of Washington School of Medicine, 1959 NE Pacific Street, Box 357650, Seattle, WA 98195, USA. singsing@u.washington.edu |
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| Abstract: | ESAT-6 is a virulence determinant in Mycobacterium tuberculosis and a member of a conserved group of proteins in a variety of other bacteria. A targeted deletion of the homologous gene in Listeria was generated, and in contrast to that observed for mycobacteria, this locus was not required for Listeria virulence. |
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