肌酸激酶MM3／MM1比值诊断急性心肌梗塞参比值的研究

目的：探讨血清肌酸激酶ＭＭ同工酶（ＣＫ－ＭＭ）亚型ＭＭ３／ＭＭ１比值诊断急性心肌梗塞的参比值。方法：应用琼脂凝胶电泳法测定了６０例ＡＭＩ，７６例非ＡＭＩ和４０例正常人血清ＣＫ－ＭＭ亚型ＭＭ３／ＭＭ１比值。结果：在诊断ＡＭＩ中ＭＭ３／ＭＭ１比值的最佳界限值为０．５，当参比值为０．５时，其敏感性为８０．０％，特异性为９３．１。诊断效率为８８．６％。结论：血清ＭＭ３／ＭＭ１比人趔ＡＭＩ诊断敏感而特异的酶

Referent values of serum isoforms of creatine kinase MM isoenzyme in the diagnosis of acute myocardial infarction

Objective:WT5BZ]To study the referent values of serum isoforms of creatine kinase MM isoenzyme(MM 3/MM 1 ratio)in the diagnosis of acute myocardial infarction(AMI).WT5HZ]Methods:WT5BZ]The changes of MM 3/MM 1 ratio in the first avaliable serum from 60 patients with AMI,76 with non-infarct and 40 normal subjects were quantified and the diagnostic accuracy for AMI in its serial referent values were evaluated.WT5HZ]Results:WT5BZ]The referent value 0.5 was the best discrimination value in the diagnosis of AMI with the sensitivity 80.0%,the specificity 93.1% and the accuracy 88.6%.WT5HZ]Conclusion:WT5BZ]These suggest the MM 3/MM 1 ratio be a sensitive and specific marker for AMI.and the prevalence and referent value were important to the diagnosis of AMI. WT5HZ]