完整结肠系膜切除术与传统结肠癌根治术治疗结肠癌疗效对比

【摘要】〓目的〓比较完整结肠系膜切除术(CME)与传统结肠癌根治手术治疗结肠癌的临床疗效。方法〓2011年1月至2012年12月期间我院收治并接受手术的结肠癌患者共38例。对照组(n=23)患者接受传统的结肠癌根治性手术,CME组(n=15)患者由同一组手术医师按照CME原则进行手术。比较两组患者手术相关指标(手术时间、术中出血量)和术后恢复情况(术后排气时间、住院时间)术后并发症发生情况、淋巴清扫。结果〓两组患者手术时间无显著性差异;CME组患者术中出血量较对照组少(P<0.05);两组患者术后排气时间、住院时间、并发症发生例数也无显著性差异;CME组患者术中清扫淋巴结数量、阳性淋巴结转移数均多于对照组患者(P<0.05)。对照组患者术后1年结肠癌复发转移病例比观察组多,但两组间差异无统计学意义(P>0.05)。结论〓CME手术能够清扫尽可能多的淋巴结,有利于降低结肠癌的复发率且不增加手术并发症。

Comparitive study between complete mesocolic excision and radical colonectomy for colon cancer

【Abstract】〓Objective〓To compare the clinical effect of complete mesocolic excision (CME) and radical colonectomy for colon cancer. Methods〓Thirty-eight patient underwent radical surgery. Between January 2011 and December 2012 were included in this study. According to the surgical procedure, 23 cases received traditionally radical colectomy (control group, n=23) and 15 cases underwent CME surgery (CME group, n=15). The clinical postoperative indicators, complications, count of dissected lymph node and the recurrence in 1-year-followed-up were compared between the two groups. Results〓The intraoperative blood loss in CME group was decreased significantly and harvested more lymph nodes when compared with control group (P<0.05), but there were not statistical differences between the two groups in operation time, postoperative exhaust time, hospital stay and complications. Conclusion〓CME could reduce the surgical blood loss and dissect much more lymph nodes, and may reduce the recurrence of colon cancer.