腹腔镜胰十二指肠切除术的临床研究:meta分析

【摘要】〓目的〓分析腹腔镜十二指肠切除术的安全性和可行性。方法〓通过关键词“腹腔镜、胰十二指肠切除术”检索知网、维普和万方等数据库以及“Laparoscopic pancreaticoduodenectomy”检索了CBM、PubMed、MEDLINE、Embase、Cochrane Library等数据库,共得到874篇相关文献,纳入本文研究的为8篇,比较分析腹腔镜胰十二指肠切除术和开放式胰十二指肠切除术的围手术期的9个参数(手术时间、术中出血量、住院时间、再次手术率、胰瘘发生率、伤口感染发生率、术后出血发生率、并发症发生率、死亡率)。结果〓腹腔镜组手术时间长于开腹组WMD=-69.96,95%CI (-83.34,56.57),P<0.05];腹腔镜组术中出血量少于开腹组WMD=363.15,95%CI(87.76, 638.54),P<0.05];腹腔镜组患者住院时间短于开腹组WMD=3.18,95%CI (2.31,4.05),P<0.05];腹腔镜组再次手术率、胰瘘发生率、伤口感染率、术后出血发生率、总并发症率、死亡率与于开腹组无明显差异。结论〓腹腔镜胰十二指肠切除术与开腹胰十二指肠切除术相比有一定的优势。

Clinical study on laparoscopic pancreaticoduodenectomy: a meta analysis

【Abstract】〓Objective〓To analyse the laparoscopic resection of duodenum of the difficulties in the process of anatomy. Methods〓Retrieved CNKI, VIP, Wan fang Data, CBM, PubMed, MEDLINE, Embase, the Cochrane Library databases by keywords "Laparoscopic pancreaticoduodenectomy; Laparoscopic pancreatic resection", received a total of 874 relevant papers (included 8 papers in this study) and compared the parameters of the laparoscopic pancreatoduodenectomy and the open pancreatoduodenectomy in perioperative period. Results〓The laparoscopic group had significantly longer operation time WMD -69.96, 95%CI(-83.34,56.57), P<0.05]and had significantly shorter intraoperative blood loss WMD 363.15, 95%CI(87.7l,638.54), P<0.05]and had significantly shorter hospital stay WMD 3.18, 95%CI(2.31,4.05), P<0.05] than those in the open group.No significantly differences were detected in the others. Conclusion〓LPD had certain advantages compared with OPD.