| 409例高血压病患者不同中医证型间心血管易损因子水平的变化 |
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| 引用本文： | 符德玉,祖亮华,辛效毅,何淑寅,张雪梅,王世红,赵彦功,周端,钱岳晟. 409例高血压病患者不同中医证型间心血管易损因子水平的变化[J]. 上海中医药大学学报, 2009, 23(3): 15-18 |
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| 作者姓名： | 符德玉 祖亮华 辛效毅 何淑寅 张雪梅 王世红 赵彦功 周端 钱岳晟 |
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| 作者单位： | 符德玉,祖亮华,辛效毅,何淑寅,张雪梅,王世红,赵彦功,FU De-yu,ZU Liang-hua,XIN Xiao-yi,HE Shu-yin,ZHANG Xue-mei,WANG Shi-hong,ZHAO Yan-gong(上海中医药大学附属岳阳中西医结合医院,上海,200437);周端,ZHOU Duan(上海中医药大学附属龙华医院,上海,200032);钱岳晟,QIAN Yue-sheng(上海交通大学医学院附属瑞金医院,上海,200025) |
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| 基金项目： | 国家中医药管理局基金 |
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| 摘 要： | 目的：探讨高血压病患者中医证型分布规律及常见心血管易损因子水平的变化。方法：对409例高血压病患者进行中医辨证分型、血压分级及危险分层；分别检测不同中医证型患者的高敏性C反应蛋白（hs-CRP）、高半胱氨酸（Hcy）、血管性血友病因子（vWF）、B型钠尿肽（BNP）的水平。结果：痰湿壅盛组血清Hcy、hs-CRP、BNP平均水平显著增高；夹痰瘀组血清Hcy、BNP水平显著高于夹瘀、夹风组；血浆vWF平均水平在阴阳两虚组最高；夹瘀组血浆vWF水平显著高于夹痰组。结论：阴阳两虚证、痰湿壅盛证及夹痰瘀患者易损因子水平较高，发生心血管事件的危险性相对较大。
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| 关 键 词： | 高血压病 中医证型 心血管易损因子 高敏性C反应蛋白 高半胱氨酸 血管性血友病因子 B型钠尿肽 |
Analysis of Cardiovascular Vulnerable Factors Among 409 Cases of EH Patients with Different Pattrens of TCM |
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| FU De-yu ZU Liang-hua XIN Xiao-yi HE Shu-yin ZHANG Xue-meiWANG Shi-hong ZHAO Yan-gong ZHOU Duan QIAN Yue-sheng. Analysis of Cardiovascular Vulnerable Factors Among 409 Cases of EH Patients with Different Pattrens of TCM[J]. Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai, 2009, 23(3): 15-18 |
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| Authors: | FU De-yu ZU Liang-hua XIN Xiao-yi HE Shu-yin ZHANG Xue-meiWANG Shi-hong ZHAO Yan-gong ZHOU Duan QIAN Yue-sheng |
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| Affiliation: | FU De-yu1 ZU Liang-hua1 XIN Xiao-yi1 HE Shu-yin1 ZHANG Xue-mei1WANG Shi-hong1 ZHAO Yan-gong1 ZHOU Duan2 QIAN Yue-sheng31.Yueyang Hospital of Integrative Chinese , Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine2.Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine3.Ruijin Hospital Affiliated to Medical Collage,Shanghai Jiaotong University |
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| Abstract: | Objective:To study the distribution law of traditional Chinese medicine(TCM) pattern in patients with essential hypertension(EH) and the levels of the cardiovascular vulnerable factors among different TCM patterns.Methods: A total of 409 EH patients underwent pattern identification,hypertension grading and risk stratification.Meanwhile,the levels of cardiovascular vulnerable factors including homocysteine(Hcy),high-sensitivity c-reactive protein(hs-CRP),von willebrand factor(vWF)and B-type natriuretic pepti... |
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| Keywords: | Essential hypertension （Eh） pattern of traditional Chinese medicine （TCM） cardiovascular vulnerable factors homocysteine（Hcy） high-sensitivity c-reactive protein（hs-CRP） yon willebrand factor（vWF） B-type natriuretic peptide （BNP） |
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