牙龈癌侵犯下颌骨SPECT/CT融合显像和CT影像的对照研究

目的探讨^99mTc-MDP SPECT/CT同机融合图像和CT在牙龈癌浸润下颌骨中的诊断价值比较。方法对18例牙龈癌患者行术前^99mTc-MDP SPECT/CT同机融合图像、CT检查，确定牙龈癌侵犯下颌骨的程度，术后病理检查结果与之对照。结果^99mTc-MDP SPECT/CT术前诊断18例牙龈癌11例肿瘤部位下颌骨放射性异常浓聚灶，经病理证实其中 1例为假阳性;3例中分化鳞癌和2例低分化鳞癌病变部位下颌骨放射性异常浓聚灶，病理显示肿瘤浸润到骨髓腔。而CT仅发现5例肿瘤侵犯下颌骨。结论^99mTc-MDP SPECT/CT图像同机融合对牙龈癌浸润下颌骨程度诊断具有重要价值。

Comparative Study of SPECT/CT Fusion Imaging and CT in Infil Trated Mandible by Gingival Carcinoma

Objective To evaluate the clinical value of ^99mTc-methylene diphosphonic acid (MDP) SPECT/CT fusion imaging and CT scanning in diagnosis of infiltrated mandible by gingival carcinoma. Methods Infiltrated mandible was analyzed in 18 cases of gingival carcinoma by ^99mTc-MDP SPECT/CT fusion images and CT, and compared with pathology findings. Results Eleven of 13 cases with well differentiated squamous cell carcinoma showed positive images, one of 11 cases was false positive images by pathology findings, 10 cases were exhibited infiltrated mandible; 5 cases with moderately differentiated and poorly differentiated squamous cell carcinoma showed positive images, and the result of pathology showed carcinoma cell had infiltrated cavum ossis of mandible. 5 of 18 cases were positive images by CT. Conclusion ^99mTc-MDP SPECT/CT fusion images is an useful method in diagnosis of infiltrated mandible by gingival carcinoma.