超声乳化IOL植入联合房角分离术治疗原发性慢性闭角型青光眼

目的:探讨超声乳化人工晶状体(intraocular lens,IOL)植入联合房角分离术治疗原发性慢性闭角型青光眼的疗效.方法:采用临床随机对照的研究方法,将临床收集的80例96眼原发性慢性闭角型青光眼患者分为观察组(40例46眼)和对照组(40例50眼).观察组给予超声乳化IOL植入联合房角分离术治疗,对照组仅给予超声乳化IOL植入术治疗.比较两组患者手术前后最佳矫正视力、眼压、视野平均缺损(mean deviation,MD)、平均视敏度值(mean sensitivity,MS)和中央前房深度改善状况,并记录患者术中、术后并发症发生状况.结果:两组患者术前最佳矫正视力、眼压、视野和中央前房深度比较,差异均无统计学意义(P>0.05);术后6mo,观察组最佳矫正视力、眼压、视野和中央前房深度与对照组相比,差异均有统计学意义(P<0.05);两组患者均无严重并发症,且差异无统计学意义(x2=2.095,P=0.351).结论:超声乳化IOL植入联合房角分离术治疗原发性慢性闭角型青光眼的疗效优于单纯超声乳化IOL植入.

Clinical study of phacoemulsification and intraocular lens implantation combined with goniosynechialysis in the treatment of primary chronic angle closure glaucoma

·AIM:To evaluate the efficacy of phacoemulsification and intraocular lens ( IOL ) implantation combined with goniosynechialysis in the treatment of primary chronic angle closure glaucoma.·METHODS: Eighty patients ( 96 eyes ) with primary chronic angle closure glaucoma were divided into observation group (40 cases, 46 eyes) and control group (40 cases, 50 eyes). The treatment group was treated with phacoemulsification, intraocular lens implantation and goniosynechialysis, while the control group was treated with phacoemulsification and intraocular lens implantation. The best corrected visual acuity, intraocular pressure, visual field mean deviation (MD), mean sensitivity ( MS) and the central anterior chamber depth of the two groups before and after the surgery were compared, and the occurrence of complications in patients with postoperative were record.·RESULTS:The best corrected visual acuity, visual field, intraocular pressure and central anterior chamber depth of the two groups before operation showed no significant differences (P>0. 05). The best corrected visual acuity, visual field, intraocular pressure and central anterior chamber depth between the groups at 6mo postoperatively showed statistically significant (P<0. 05). There was no serious complications in the two groups, and the difference between the two groups showed no statistically significant (x2=0. 351, P=2. 095).· CONCLUSION: The application of the phacoemulsification and intraocular lens implantation combined with goniosynechialysis in the treatment of primary chronic angle closure glaucoma is more effective than the simple use of phacoemulsification and intraocular lens implantation.