中西医结合治疗非增生性糖尿病视网膜病变的临床疗效

目的:观察中西医结合治疗非增生性糖尿病视网膜病变的临床疗效.方法:非增生性糖尿病视网膜病变患者90例90眼,随机分为西药治疗组(30例30眼)、中药治疗组(30例30眼)以及中西医结合治疗组(30例30眼).三组患者基础治疗相同,西药治疗组采用羟苯磺酸钙胶囊治疗,中药治疗组采用辨证分型论治,中西医结合治疗组即在西药治疗基础上结合辨证分型论治.治疗6个疗程后,记录并分析所有患者的临床疗效.结果:经治疗后,中西医结合治疗组的总有效率为86%,明显高于西药组的57%和中药组的60%(均P<0.05);治疗后中西医结合治疗组的视力改善明显优于西药组与中药组(均P<0.05);治疗后中西医结合治疗组黄斑区视网膜水肿吸收情况及视功能恢复情况均明显优于西药组和中药组(均P<0.05);治疗后中西医结合治疗组中医症状积分下降较西药组与中药组均更加明显(均P<0.05).结论:中西医结合治疗非增生性糖尿病视网膜病变疗效显著.

Clinical efficacy of integrative therapy in the treatment of non-proliferative diabetic retinopathy

AIM: To study the clinical efficacy of integrative therapy in the treatment of non-proliferative diabetic retinopathy.

METHODS: Ninety patients(90 eyes)in our hospital with non-proliferative diabetic retinopathy were randomly divided into three groups. All three groups were treated with diabetes drugs to control blood sugar. The first group was treated with western medicine, the second group was treated with Chinese medicine decoction Traditional Chinese Medicine(TCM)treatment, and the third group was treated with the combination of those two methods. All patients were recorded and analyzed changes of clinical effects after 6 courses of treatment.

RESULTS: After 6 courses of treatment, the total efficacy rate of the third group was 86%, markedly higher than that of the first group(57%, P<0.05)as well as the second group(60%, P<0.05). The integrative group improved more markedly in terms of vision, macular edema absorption, and ERG b-wave amplitude restoration, the difference being statistically significant(P<0.05)when compared to the first and the second group.

CONCLUSION: Integrative treatment of diabetic retinopathy could effectively improve the therapeutic effect in patients with non-proliferative retinopathy.