Measurement of bone mineral density of lumbar spine and whole body in low-birth-weight infants: comparison of two methods |
| |
Authors: | Hiroyuki Ichiba Chie Hirai Mutsuko Fujimaru Haruo Shintaku Tsunekazu Yamano Masahisa Funato |
| |
Institution: | (1) Department of Pediatrics, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abenoku, Osaka 545-8586, Japan, JP;(2) Department of Pediatrics, Yodogawa Christian Hospital, Osaka, Japan, JP |
| |
Abstract: | In the present study, we compared lumbar spinal and whole-body bone mineral density (BMD) measurements to determine which
is more suitable for evaluating the bone mineral status of low-birth-weight (LBW) infants. Lumbar spinal and whole-body BMD
were assessed simultaneously in a prospective series including 152 Japanese LBW infants (birth weight 453–2400 g, gestational
age 24–38 weeks) from the age of 40 weeks post-conception to 2 years of age. Lumbar spinal BMD at 40 weeks post-conception
was significantly correlated with birth weight (r = 0.74; P < 0.0001), but whole-body BMD was not correlated with birth weight. No correlation was found between lumbar spinal and whole-body
BMD at 40 weeks post-conception. However, after 40 weeks post-conception, a significant correlation was found between lumbar
spinal and whole-body BMD (r = 0.65; P < 0.0001). For infants with a body weight of 4 kg or less at the time of measurement, no correlation was found between lumbar
spinal and whole-body BMD. However, for infants with a body weight above 4 kg, a significant correlation was found between
lumbar spinal and whole-body BMD (r = 0.65; P < 0.0001). Thus, lumbar spinal BMD is more suitable than whole-body BMD for evaluation of the bone mineral status of LBW
in early infancy. Therefore, lumbar spinal BMD should be used for serial evaluation of changes in the bone mineral status
of LBW infants.
Received: April 6, 2000 / Accepted: June 16, 2000 |
| |
Keywords: | dual-energy X-ray absorptiometry bone mineral density low-birth-weight infant |
本文献已被 PubMed SpringerLink 等数据库收录! |
|