| 左卡尼汀治疗糖尿病周围神经病变的临床疗效 |
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| 引用本文： | 王宏利,樊东升,洪天配,高洪伟. 左卡尼汀治疗糖尿病周围神经病变的临床疗效[J]. 中华内分泌代谢杂志, 2008, 24(6) |
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| 作者姓名： | 王宏利 樊东升 洪天配 高洪伟 |
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| 作者单位： | 1. 北京大学糖尿病中心神经病变研究室,北京大学第三医院神经内科,100083
2. 北京大学糖尿病中心神经病变研究室,内分泌科,北京大学第三医院神经内科,100083 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | 100例2型糖尿病周围神经病变的患者随机分为对照组和左卡尼汀组(1 000 mg,tid),服药16周后,左卡尼汀组患者密歇根神经病变筛查量表评分,视觉对等评分均有明显改善,定量感觉检查显示热感觉和热痛觉较治疗前有明显改善(均P<0.05),提示左卡尼汀对糖尿病周围神经病变尤其对疼痛有一定的治疗作用.
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| 关 键 词： | 左卡尼汀 糖尿病性神经病变 |
Clinical efficacy of L-carnitine in treating diabetic peripheral neuropathy |
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| WANG Hong-li,FAN Dong-sheng,HONG Tian-pei,GAO Hong-wei. Clinical efficacy of L-carnitine in treating diabetic peripheral neuropathy[J]. Chinese Journal of Endocrinology and Metabolism, 2008, 24(6) |
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| Authors: | WANG Hong-li FAN Dong-sheng HONG Tian-pei GAO Hong-wei |
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| Abstract: | One hundred patients with type 2 diabetic neuropathy were divided into L-carnitine group and control group with 50 eases in each group. Data showed significant improvements in clinical symptoms scores, visual analogue scale and quantitative sense test after 16-week L-earnitine treatment (all P < 0.05). The study demonstrates that L-earnitine has affirmative effect on patients with diabetic neuropathy, especially in alleviating pain. |
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| Keywords: | Carnitine Diabetic neuropathies |
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