Negative pressure wound therapy compared with conventional wound dressings for closed incisions in orthopaedic trauma surgery: A meta‐analysis |
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| Authors: | Weiwei Xie Lingyan Dai Yameng Qi Xixi Jiang |
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| Affiliation: | 1. Department of Operation Room, The First People''s Hospital of Wenling, Wenling China ; 2. Ambulatory Surgery Center, Wuhan Children''s Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, (Wuhan Maternal and Children''s Healthcare Center), Wuhan China ; 3. Department of Dermatology, Second Hospital Affiliated to Tianjin Medical University, Tianjin China |
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| Abstract: | We performed a meta‐analysis to evaluate the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. A systematic literature search up to October 2021 was done and 12 studies included 3555 subjects with closed incisions in orthopaedic trauma surgery at the start of the study: 1833 of them were provided with negative pressure wound therapy and 1722 were conventional wound dressings. They were reporting relationships about the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. We calculated the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) to assess the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery using the dichotomous and continuous methods with a random or fixed‐effect model. Negative pressure wound therapy had significantly lower deep surgical site infection (OR, 0.65; 95% CI, 0.48–0.88, P = .005), superficial surgical site infection (OR, 0.23; 95% CI, 0.11–0.49, P = .31), and wound dehiscence (OR, 0.41; 95% CI, 0.21–0.80, P = .009) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. However, negative pressure wound therapy had no significant effect on the length of hospital stay (MD, 0.29; 95% CI, −2.00‐ 2.58, P = .80) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. Negative pressure wound therapy had significantly lower deep surgical site infection, superficial surgical site infection, and wound dehiscence; however, negative pressure wound therapy had no beneficial effect on the length of hospital stay compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. Further studies are required to validate these findings. |
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| Keywords: | closed incisions conventional wound dressing length of hospital stay negative pressure wound therapy orthopaedic trauma surgery |
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