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奥美拉唑注射液治疗消化性溃疡上消化道出血62例疗效分析
引用本文:吴木生,张庆年,吴瑗,王家顺. 奥美拉唑注射液治疗消化性溃疡上消化道出血62例疗效分析[J]. 职业与健康, 2009, 25(20): 2236-2237
作者姓名:吴木生  张庆年  吴瑗  王家顺
作者单位:1. 广东省湛江市职业病防治所,524018
2. 广东医学院附属医院
摘    要:目的探讨奥美拉唑治疗上消化道消化性溃疡出血的临床疗效。方法使用注射用奥美拉唑治疗消化性溃疡出血62例为治疗组,过去使用西咪替丁针剂治疗相似病人58例为对照组。结果治疗组显效、有效、无效率分别为24.19%、72.58%、3.23%,对照组分别为13.79%、60.34%、25.86%。2组比较,差异有统计学意义(x^2=13.20,P〈0.01)。结论2种药物均适用于消化性溃疡出血的病人,但注射用奥美拉唑疗效更佳。

关 键 词:奥美拉唑  西眯替丁  消化性溃疡  上消化道出血

Omeprazole Injection in Treatment of Peptic Ulcer and Upper Gastrointestinal Hemorrhage:Efficacy Analysis of 62 Cases
WU Mu-sheng,ZHANG Qing-nian,WU Yuan,WANG Jia-shun. Omeprazole Injection in Treatment of Peptic Ulcer and Upper Gastrointestinal Hemorrhage:Efficacy Analysis of 62 Cases[J]. Occupation and Health, 2009, 25(20): 2236-2237
Authors:WU Mu-sheng  ZHANG Qing-nian  WU Yuan  WANG Jia-shun
Affiliation:WU Mu-sheng , ZHANG Qing-nian, WU Yuan,et al. ( Zhenjiang occupational disease dispensary, Guangdong , 524018, China )
Abstract:[ Objective] To investigate the clinical efficacy of Omeprazole in treatment of peptic ulcer hemorrhage. [ Methods ] 62 cases with peptic ulcer hemorrhage with omeprazole injection treatment were selected as treatment group, the similar 58 cases who had received cimetidine injection treatment as control group. [Results]Markedly effective, effective, ineffective of 24.19% , 72.58% , 3.23% respectively in treatment group, compared that in the control group ( 13.79%, 60.34% , 25.86% ) , the differences were significant ( X^2 = 13.20, P 〈 0.01 ). [ Conclusion ] Either of the 2 drugs is applicable to patients with peptic ulcer hemorrhage, but a better effect of omeprazole injection.
Keywords:Omeprazole  Cimetidine  Peptic ulcer  Upper gastrointestinal hemorrhage
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