| 奥美沙坦:一种新的血管紧张肽Ⅱ受体拮抗剂 |
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| 引用本文： | 陶霞,刘皋林. 奥美沙坦:一种新的血管紧张肽Ⅱ受体拮抗剂[J]. 中国新药与临床杂志, 2003, 22(6): 368-370 |
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| 作者姓名： | 陶霞 刘皋林 |
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| 作者单位： | 上海长征医院,药学部,上海,200003 |
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| 摘 要： | 奥美沙坦 (olmesartan)是最新的血管紧张肽Ⅱ受体 (AT1)拮抗剂 ,对不同程度的高血压均有很好的降压作用 ,病人对其亦有很好的耐受性。本文对该药的药效学、药动学和临床应用等研究作一综述
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| 关 键 词： | 高血压 药效学 抗高血压药 受体,血管紧张肽 血管紧张肽Ⅱ 奥美沙坦 血管紧张肽Ⅱ受体拮抗剂 |
| 文章编号： | 1007-7669(2003)06-0368-03 |
Olmesartan:a novel angiotensin Ⅱ receptor antagonist |
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| TAO Xia,LIU Gao lin. Olmesartan:a novel angiotensin Ⅱ receptor antagonist[J]. Chinese Journal of New Drugs and Clinical Remedies, 2003, 22(6): 368-370 |
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| Authors: | TAO Xia LIU Gao lin |
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| Abstract: | Olmesartan is the most recently developed angiotensin Ⅱ receptor antagonist. The efficacy of olmesartan medoxomil in the treatment of various stages of hypertension has been demonstrated in well designed clinical trials. Olmesartan is well tolerated and its adverse reaction is similar to that of placebo. This paper reviews the progress in the pharmacodynamics, pharmacokinetics and clinical studies of olmesartan. |
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| Keywords: | hypertension pharmacodynamics antihypertensive agents receptors, angiotensin angiotensin Ⅱ olmesartan angiotensin Ⅱ receptor antagonist |
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