| 50例儿童急性淋巴细胞白血病三年后随访结果 |
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| 引用本文： | 符仁义,罗春华,廖清奎,李钦伯,贾苍松.50例儿童急性淋巴细胞白血病三年后随访结果[J].四川大学学报(医学版),1995(2). |
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| 作者姓名： | 符仁义 罗春华 廖清奎 李钦伯 贾苍松 |
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| 作者单位： | Department of Pediatric Hematology，The Second Affiliated Hospital |
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| 摘 要： | 对５０例儿童急性淋巴细胞白血病在平均３年零３个月后作了随访小结。结果：１９例放弃治疗（３８％）；断续治疗１年者８例，其中２例已自动停药２～３年并且无病生存，余６例失访；２３例能长期坚持治疗，其中３例死于感染，１１例持续完全缓解至今，９例复发。在接受治疗的病例中，３年零３个月生存率为４２％（１３／３１）。统计结果表明，初诊时外周血淋巴细胞糖皮质激素受体水平低者复发率高。
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| 关 键 词： | 儿童急性淋巴细胞白血病，随访，糖皮质激素受体 |
A 3-Year Follow-up Study of 50 Children with Acute Lymphoblastic Leukemia |
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| Fu Renyi,Luo Chunhua,Liao Qingkui,Li Qinbo,Jia Changsong.A 3-Year Follow-up Study of 50 Children with Acute Lymphoblastic Leukemia[J].Journal of West China University of Medical Sciences,1995(2). |
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| Authors: | Fu Renyi Luo Chunhua Liao Qingkui Li Qinbo Jia Changsong |
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| Abstract: | Fifty children with acute lymphoblasticleukemia were followed up for an average period of3 years. The results showed that 19 (38%) caseswere given up after diagnosis. Eight patients only re-ceived treatment irregularly for l year;among them,2discontinued therapy by themselves for 2-3years andsurvived free of events,and 6 were lost,Twenty-three received treatment regularly; among them,3died of infection,11 were in continuously complete re-mission and 9 experienced relapse.The total disease-free survival rate for mean 3 years is 42%(13/31),exclusive of the 19 given up cases. Statistical analysisindicates a higher relapse rate in those cases with low-er initial glucocorticoid receptors(GCR) of peripheralblood lymphoeytes. |
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| Keywords: | Children acute lymphoblastic leukemia Follow-up Glucocorticoid receptor |
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