支气管激发试验与发病时间的相关性分析

目的 探讨支气管激发试验与发病时间的相关性.方法 选取2013-2014年我院107例临床表现为不明原因的咳嗽及喘憋等症状患者,均行支气管激发试验,进一步根据其发病时间分为急性病程（＜3周）、亚急性病程（3～8周）、慢性病程（＞8周）3组,比较3组支气管激发试验的阳性率.结果 在所有107例患者中,激发试验阳性患者36例,阴性71例.其中急性病程16例,亚急性病程36例,慢性病程55例.在急性病程、亚急性病程、慢性病程中支气管激发试验阳性率分别为56.3％ （9/16）、36.1％ （13/36）、23.6％ （13/55）,3组比较差异有统计学意义（x2=6.275,P＜0.05）.且急性病程中激发试验的阳性率高于慢性病程（x2 =6.165,P＜0.05）.支气管激发试验的阳性率与发病时间正相关,Pearson相关系数为0.239（P＜0.05）.结论 支气管激发试验的阳性率与发病时间具有相关性,对急性病程中阳性患者应加强监测及随访.

The relationship of bronchial provocation tests and the onset of the disease

Objective To investigate the correlation between bronchial provocation tests and the onset of the disease.Methods One hundred and seven patients who hospitalized in General Hospital of China Aviation from 2013-2014 were selected as our subjects.They all were with unexplained symptoms such as cough and asthma suppress.All the patients were performed bronchial provocation tests.In accordance with the onset time,patients were divided into acute （〈 3 weeks）,subacute （3-8 weeks） and chronic （〉 8 weeks） groups.The positive rates of bronchial provocation test of three groups were compared.Results Of all 107 patients,36 patients were positive and 71 were negative in terms of bronchial provocation test.The cases with acute,subacute and chronic disease history were 16,36 and 55 respectively.The positive rate of bronchial provocation tests in different onset were 56.3% （9/16）,36.1% （13/36）,23.6% （13/55） respectively,and there was statistics significant difference（x2 =6.275,P 〈 0.05）.The positive rate of bronchial provocation tests in acute group was higher than that in chronic group （x2 =6.165,P 〈 0.05）.There was positive correlation between the positive rate of bronchial provocation tests and the onset,and the correlation coefficient Pearson was 0.239 （P 〈0.05）.Conclusion There is a correlation between the positive rate of bronchial provocation tests and the onset.We should strengthen the monitoring in patients with acute onset and follow-up.