川崎病61例临床分析

目的分析川崎病（KD）尤其是不完全川崎病（IKD）的临床表现及实验室检查特点,以早期诊治,减少冠状动脉损害的发生。方法对2003年7月～2011年7月我院儿科收治住院的川崎病患儿61例,其中典型川崎病（KD）45例和不完全川崎病（IKD）16例临床资料进行回顾性分析。结果 61例KD中男36例,女25例,男女比例为1.44：1,其中5岁以下发病占80.3%I,KD占26.2%。典型KD和IKD 2组病例在皮疹、眼球结膜充血、口唇及口腔黏膜改变、四肢硬肿脱皮、颈淋巴结肿大方面比较,差异有统计学意义;在实验室检查及冠状动脉损害方面,差异无统计学意义。结论 IKD与典型病例的冠状动脉损害发生率相近,一旦疑为川崎病,应尽早做超声心动图检查。

Clinical analysis of 61 cases of Kawasaki disease

Objective To analyze the clinical characteristics and laboratory tests of the children with Kawasaki disease（KD）,especially incomplete KD（IKD）.Methods Clinical data of 61 cases of KD in our hospital from July 2003 to July 2011 were retrospectively analyzed.45 cases were diagnosed as typical KD,and 16 cases as incomplete KD.Clinical data of typical and incomplete KD were compared.Results Among the 61 KD patients,36 were male and 25 female.The male-female ratio was 1.44：1.80.3% of the cases occurred in children younger than 5 years of age.26.2% of the cases were incomplete KD.There were significant differences in rash,non-exudative conjunctivitis,oral mucosal changes,changes in the extremities,cervical lymphadenopathy between typical KD and incomplete KD,but not in laboratory tests and the damage to coronary arteries.Conclusion The incidence of coronary problem is similar between typical cases and incomplete KD cases.Once Kawasaki disease is suspected,ultrasonic cardiograph should be performed early.