脑梗死后抑郁症临床分析

目的：探讨急性脑梗死病人抑郁症的发生率及治疗方法。方法：用汉密尔顿抑郁量表（HAMD）评估112例急性脑梗死病人，对有抑郁症者应用盐酸舍曲林（郁乐复）或盐酸帕罗西汀（赛乐特）治疗。结果：112例病人中有抑郁症者47例，发病率41．96％，治疗后好转率85．1％，治疗后HAMD积分较治疗前明显减少（P＜0．01），结论：急性脑梗死后抑郁症的发生率高，应用特异性，选择性5－羟色胺再摄取抑制剂治疗疗效显著。

A clinical analysis of depression in patients after cerebral infarction

Objective To study the frequencies and therapeutic effect of depression after cerebral infarction.Methods 112 patients with acute cerebral infarction were assessed with hamilton depreesion scale(HAMD).The patients with depression were treated with antidepression drugs such as Sertraline and Paroxetine.Results In the 112 patients,depression were 41.96%(47/112),recovery rates of treatment were 85.1%,in which the scores of HAMD after treatment were much less than before treatment(P<0.01).Conclusion The frequencies of depression in patients with cerebral infarction are very high,and the apparent effect of selective serotonin reuptake inhibitors are obvious.