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松果菊中有效成分菊苣酸的含量测定
引用本文:王弘,刘文芝,鲁晓蕾,陈世忠,艾铁民. 松果菊中有效成分菊苣酸的含量测定[J]. 中国中药杂志, 2002, 27(6): 418-420
作者姓名:王弘  刘文芝  鲁晓蕾  陈世忠  艾铁民
作者单位:北京大学,药学院,北京,100083
基金项目:国家中医药管理局重大科技开发项目[国中医药发 (2 0 0 1) 10号 ]
摘    要:目的 :通过测定松果菊中菊苣酸的含量、分析松果菊有效成分的变化规律。方法 :采用反相HPLC法测定。结果 :松果菊根的菊苣酸含量是 5月的幼苗期最高 ,花的菊苣酸含量是 7月中旬的盛花期最高 ,茎的菊苣酸含量普遍偏低 ;地上部分药材的菊苣酸含量是 7月中旬的盛花期最高。结论 :建立了稳定、可靠的菊苣酸的含量测定方法。松果菊中菊苣酸的含量变化规律对于确定药材的药用部位及最佳采收期具有指导意义。

关 键 词:松果菊  菊苣酸  含量  HPLC
文章编号:1001-5302(2002)06-0418-03
收稿时间:2001-09-11
修稿时间:2001-09-11

Determination of Cichoric Acid in Echinacea purpuea
WANG Hong;LIU Wen zhi;LU Xiao lei;CHEN Shi zhong;AI Tie min. Determination of Cichoric Acid in Echinacea purpuea[J]. China Journal of Chinese Materia Medica, 2002, 27(6): 418-420
Authors:WANG Hong  LIU Wen zhi  LU Xiao lei  CHEN Shi zhong  AI Tie min
Affiliation:School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Abstract:Objective: To analyze the natural change rule of active components of E. purpuea by measuring content of cichoric acid. Method: Reverse HPLC method was used. Result: The maximum cichoric acid content of the roots occured in seedling age of May, and that of the flowers occured in blooming stage of mid July, but cichoric acid in stems was generally low anyway. The maximum content of cichoric acid in the plant above ground occured in the blooming stage of mid July. Conclusion: The measuring method of content of cichoric acid is successful and reliable. The optimum stage of harvest in Echinacea purpuea shoud be guided by natural change rule of cichoric acid content.
Keywords:Epurpuea  cichoric acid  content  HPLC
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