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Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis
Authors:Giuseppe Filardo  Elizaveta Kon  Roberto Buda  Antonio Timoncini  Alessandro Di Martino  Annarita Cenacchi  Pier Maria Fornasari  Sandro Giannini  Maurilio Marcacci
Affiliation:(1) Biomechanics Laboratory—III Clinic, Rizzoli Orthopaedic Institute, Via Di Barbiano 1/10, 40136 Bologna, Italy;(2) II Clinic, Rizzoli Orthopaedic Institute, Bologna, Italy;(3) Immunohematology and Transfusion Medicine Service, Rizzoli Orthopaedic Institute, Bologna, Italy
Abstract:

Purpose  

Platelet-rich plasma (PRP) therapy is a simple, low-cost and minimally invasive method that provides a natural concentrate of autologous blood growth factors (GFs) that can be used to enhance tissue regeneration. In a previous analysis of a 12-month follow-up study, promising results were obtained when treating patients affected by knee degeneration with PRP intra-articular injections. The main purpose of this study was to investigate the persistence of the beneficial effects observed.
Keywords:
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