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Chemical composition and larvicidal activity of several essential oils from Hypericum species from Tunisia |
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| Authors: | Zyed Rouis Ali Laamari Nabil Abid Ameur Elaissi Pier Luigi Cioni Guido Flamini Mahjoub Aouni |
| Affiliation: | 1. Laboratory of Transmissible Diseases and Biological Active Substances, Faculty of Pharmacy, University of Monastir, Avenue Avicenne, 5000, Monastir, Tunisia 2. Laboratory of Histology, Cytology, and Genetics, Faculty of Medicine, University of Monastir, 5000, Monastir, Tunisia 3. Pharmacognosy Laboratory, Faculty of Pharmacy, University of Monastir, Avenue Avicenne, 5000, Monastir, Tunisia 4. Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126, Pisa, Italy |
| Abstract: | The chemical composition of the essential oils extracted from some Tunisian Hypericum species and their larvicidal activity against Culex pipiens larvae were evaluated. The chemical compositions of the essential oils from the aerial plant parts were analyzed using gas chromatography–mass spectrometry. One hundred and thirty-four compounds were identified, ranging between 85.1 and 95.4 % of the oil's composition. The components were monoterpene hydrocarbons, oxygenated monoterpenes, sesquiterpene hydrocarbons, oxygenated sesquiterpenes, non-terpenic hydrocarbons, and others. The larvicidal activity of the essential oils was evaluated using a method recommended by WHO. Larvicidal tests revealed that essential oils from the Hypericum species have a significant larvicidal activity against C. pipiens, with LC50 ranging between 102.82 and 194.70 ppm. The most powerful essential oils against these larvae were Hypericum tomentosum and Hypericum humifusum samples, followed by the essential oil of Hypericum perforatum. |
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