阿尔茨海默病患者能量、营养素摄入量及营养状况调查

摘要：目的调查分析阿尔茨海默病患者每日能量、营养素摄入量和身体营养状况及其对发病的影响。方法采用病例-对照研究，选择阿尔茨海默病85例为病例组，相匹配的正常人82例为对照组，所有研究对象均按调查要求填写基本信息表和膳食记录调查表，采用人体成分分析仪测量体质量、体质指数、脂肪重量、体脂百分比和瘦组织重量等多项指标。结果病例组体质指数平均为23.58±5.88、三头肌皮褶厚度为（17.24±3.65）cm、脂肪重量为（16.41±2.41）kg和体脂百分比为（25.94±3.79）%，均明显低于对照组（P<0.05）；病例组平均每日每公斤体质量能量和蛋白质的摄入量均明显高于对照组（P<0.05）；平均每日能量、蛋白质、脂肪和碳水化合物摄入量，两组之间差异无统计学意义（P>0.05）。结论膳食能量、营养素摄入量和身体营养状况是阿尔茨海默病的重要影响因素。

Intake of energy nutrients and the nutritional status of patients with Alzheimer's disease

To explore the intake of energy nutrients and the nutritional status of patients with Alzheimer′s disease and to explore their roles on Alzheimer′s disease. MethodsEighty-five patients with Alzheimer′s disease were selected as the case group and eighty two health aged adults served as the control group. Basic information and intake of food in the two groups were investigated, data of body weight, body mass index (BMI) and body composition were detected by body composition analyzer (Biospace Inbody3.0), also triceps skin fold thickness (TST), upper arm circumference and lean weight were collected. ResultsIn the case group, average of BMI was 23.58±5.88, triceps skin-fold thickness (TST) was (17.24±3.65) cm, weight of the body fat was (16.41±2.41)kg and percentage of fat was (25.94%±3.79%), which were all significantly lower than those of the control group(P<0.05). Also intake of calories and protein per body weight kilogram per day were significantly higher in the case group than those in the control group (P<0.05), but there were no significant differences in intake of calories, protein, fat and carbohydrate per day in the two groups (P>0.05). ConclusionIntake of energy nutrients and nutritional status are influencing factors for Alzheimer′s disease.