冷冻外科中组织冻结的实验和理论研究

冷冻外科中组织冻结过程的温度场和温度梯度分布，达到要求温度所需的理论冷量等热力参数对深入分析冷冻损伤机理，指导手术过程十分重要。本文对３．４ｍｍ冷刀在明胶（模拟生物组织）中的冻结过程进行了实验。并用焓法建立模拟生物组织冻结过程的多维数学模型，用有限元法进行了救解。计算结果与实验值符合较好。该模型和方法可用于预测各种壁面降温规律下组织冻结范围、各点温度梯度和理论冷量。

Experimental and theoretical studies of the freezing processing in cryosurgery

The thermal characters such as temperature field, temperature grads and cooling power are very important for sur geons to estimate and improve curative effect. The freezing experiment around a 3.4mm cryoprobe was conducted and a multi dimensional numerical model based on enthalpy method and solved by finite element scheme for the freezing process of simu lative biological tissues during cryosurgery is presented. The results of the numerical solution were validated against experimen taal data .The utility of the numerical solution for the design and application of c ryodevices is demonstrated.