| 血浆内皮素—1与糖尿病视网膜病变发病关系的临床研究 |
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| 引用本文： | 何剑峰 鲍连云. 血浆内皮素—1与糖尿病视网膜病变发病关系的临床研究[J]. 眼科, 1997, 6(4): 228-229 |
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| 作者姓名： | 何剑峰 鲍连云 |
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| 作者单位： | 青岛医学院附属医院眼科!广西柳州市第一人民医院眼科，545001，青岛医学院附属医院眼科!连云港市人民医院眼科，青岛医学院附属医院眼科 |
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| 摘 要： | 为探索血浆内皮素－１（ＥＴ１）与糖尿病视网病变发生发展的关系，我们用放射免疫法对确诊的糖尿病视网病变患者４４例，糖尿病无视网病变患者１２例以及下沉对照组３０例血浆ＥＴ１水平进行了检测及分析，结果糖尿病患者血浆ＥＴ１浓度显著高于正常对照组，而糖多病变组又明显高于糖再会我视网的变组，其中以增型糖尿 病视网膜病变组血浆ＥＴ１浓度最高。表明糖尿病视网膜病变的发生发展与血浆中ＥＴ１浓度的增加有关。
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| 关 键 词： | 糖尿病 视网膜病变 内皮素－1 病理 |
Clinical study of ET_1 level in plasma from patients with diabetic retinopathy |
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| He Jianfeng Ophthalmol CHN. -. Clinical study of ET_1 level in plasma from patients with diabetic retinopathy[J]. Ophthalmology in China, 1997, 6(4): 228-229 |
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| Authors: | He Jianfeng Ophthalmol CHN. - |
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| Affiliation: | He Jianfeng Ophthalmol CHN. -1997,6 |
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| Abstract: | To study the relation between the level of endothelin-1 (ET1) in plasma and the occurrence of diabetic retinopathy (DR), levels of ET1 in plasma were investigated by radio-immunoassay (RIA) in 44 diabetics with DR, 22 diabetics with no DR (NDR) and 30 sex and age matched normal subjects. We found that the level of ET1 in diabetics group was markedly higher than that in the control group;the level of ET1in DR group was higher than that in NDR group;the level of ET1 in proliferative DR(PDR) was the highest.The above results suggested that the occurrence and development of DR were connected with the elevation of levels of ET1 in plasma. |
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| Keywords: | Diabetic retinopathy Endothelin-1 |
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