Interacting populations affecting proliferation of leukemic cells in culture |
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Authors: | Aye, MT Till, JE McCulloch, EA |
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Abstract: | Peripheral blood cells from three patients with acute leukemic have been studied using a suspension culture method previously described.1 Cytogenetic studies in two of the patients permitted the identification of the proliferating cells in the cultures as being derived from a leukemic population. Cell separation studies using velocity sedimentation supported the concept that growth of the leukemic cells in culture is dependent on an interaction between two populations of leukemic cells. |
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