脑卒中急性期血脂动态变化

对４１例急性脑卒中患者（其中脑出血３１例，脑梗塞１０例）的血清甘油三酯（ＴＧ）、总胆固醇（ＴＣ）、高密度脂蛋白胆固醇（ＨＤＬ－ｃ）、脂蛋白（ａ）「Ｌｐ（ａ）」、纤维蛋白原（Ｆｇ）、载脂蛋白Ａ－１（ＡｐｏＡ－Ｉ）和ＡｐｏＢ进行动态观察，结果表明脑出血患者急性期ＨＤＬ－ｃ及其亚组分、ＡｐｏＡ－Ｉ和ＴＣ水平进行性降低，２周时降至最低水平，血清Ｆｇ和Ｌｐ（ａ）水平升高，１周时达高峰，而ＴＧ和ＡｐｏＢ水平无

Dynamic changes of serum lipids in patients with acute stroke]

The dynamic changes of the serum levels of total cholesterol(TC), triglyceride(TG), high density lipoprotein-cholesterol(HDL-c) and subfraction(HDL2-c), apolipoprotein(Apo) A-I, ApoB, lipoprotein(a)Lp(a)] and fibrinogen(Fg) were measured in forty-one patients with acuteincluding 31 cerebral hemorrhagic patients(ICH), and 10 cerebral infraction patients(CI)]. The results showed that the serum levels of HDL-c and subfractions, ApoA-I and TC gradually decreased in ICH during acute phase, and reduced to the lowest level on the fourteenth day, while the levels of TG and ApoB had no obvious change, the serum levels of Fg and Lp(a) increased to the highest level on the seventh day. The serum levels of Lp(a), ApoB and TG had no obvious change in CI during acute phase, and the serum levels of TC, HDL-c and subfraction, ApoA-I decreased, while the level of Fg increased in CI, but there was no statistical significance. It is suggested that Lp (a) is a positive acute reactive lipoprotein in ICH, and HDL and ApoA-I are negative acute reactive substances in ICH and CI.