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术后镇痛中氟比洛芬酯对吗啡用量及效果的影响
引用本文:吴卫东,姜春南,邵钢,尹丹琴,韦宁仙.术后镇痛中氟比洛芬酯对吗啡用量及效果的影响[J].江苏医药,2011,37(15).
作者姓名:吴卫东  姜春南  邵钢  尹丹琴  韦宁仙
作者单位:南通大学附属丹阳医院麻醉科,丹阳市,212300
摘    要:目的评价术后镇痛中氟比洛芬酯对吗啡用量和效果的影响。方法手术患者60例,随机均分为三组。术后镇痛:A组,吗啡40 mg+阿扎司琼10 mg+生理盐水100 ml;B组用氟比洛芬酯50 mg超前镇痛,术后吗啡40 mg+阿扎司琼10 mg+生理盐水100 ml;C组氟比洛芬酯100 mg+阿扎司琼10 mg+吗啡40 mg+生理盐水100 ml。观察术后吗啡的用量,患者自控镇痛(PCA)总次数,术后4、8、12、24 h的VAS疼痛评分。结果与A组比较,B、C组术后122、4 h吗啡用量减少,PCA总次数减少,VAS评分降低(P<0.05)。结论氟比洛芬酯50 mg超前镇痛或镇痛泵中氟比洛芬酯100 mg与吗啡配伍,具有较好的镇痛效果,可减少吗啡用量。

关 键 词:氟比洛芬酯  吗啡  术后镇痛  

Effects of flurbiprofen on the analgesia and requirment of morphine during postoperative analgesia
WU Weidong,JIANG Chunnan,SHAO Gang,et al..Effects of flurbiprofen on the analgesia and requirment of morphine during postoperative analgesia[J].Jiangsu Medical Journal,2011,37(15).
Authors:WU Weidong  JIANG Chunnan  SHAO Gang  
Institution:WU Weidong,JIANG Chunnan,SHAO Gang,et al.Department of Anesthesia,Affiliated Danyang Hospital,Nantong University,Danyang 212300,CHINA
Abstract:Objective To evaluate the effects of flurbiprofen on the analgesia and requirement of morphine during patient-controlled intravenous analgesia(PCIA).Methods PCIA was performed in 60 patients underwent surgeries,who were randomly and equally divided into 3 groups of A(morphine 40mg+azasetron 10mg+normal saline 100ml),B(50mg flurbiprofen preemptive analgesia and postoperative morphine 40mg+azasetron 10mg+normal saline 100ml),and C(flurbiprofen 100mg+azasetron 10mg+morphine 40mg+normal saline 100ml).The morphi...
Keywords:Flurbiprofen  Morphine  Postoperative analgesia  
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