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米非司酮用于紧急避孕的临床观察
引用本文:韩学军 翁梨驹. 米非司酮用于紧急避孕的临床观察[J]. 中华妇产科杂志, 1996, 31(9): 526-529
作者姓名:韩学军 翁梨驹
作者单位:首都医科大学附属红十字朝阳医院妇产科,国家计划生育委员会科学技术研究所
摘    要:目的:探讨米非司酮单独应用与以炔失碳失碳酯合并应用的紧避孕效果。方法:将避孕失败或无保护性生活后72小时内有的300例健康妇女随机分为3组。组I(100例),口服米非司酮25mg,12小时后重复1次,组Ⅱ(99例),口服米非司酮25mg1次;组Ⅲ(101例),1次口服米非司司酮25mg及双炔失碳酯7.5mg。结果:组I无妊娠发生,组Ⅱ、组Ⅲ各妊娠1例;避孕有效率3组依次为100.0%,83.8%,

关 键 词:米非司酮 去甲雄烷类 避孕 药物避孕

EmergencyContraceptionwithMifepristoneandAnordrin
HanXuejun,WengLiju,XiaoBil-ian.ChaoyangHospital,CapitalUniversityofMedicalScience,Beijing. EmergencyContraceptionwithMifepristoneandAnordrin[J]. Chinese Journal of Obstetrics and Gynecology, 1996, 31(9): 526-529
Authors:HanXuejun  WengLiju  XiaoBil-ian.ChaoyangHospital  CapitalUniversityofMedicalScience  Beijing
Affiliation:HanXuejun*,WengLiju*,XiaoBil-ian.*ChaoyangHospital,CapitalUniversityofMedicalScience,Beijing100020
Abstract:Objective:Tostudytheeficacyofmifepristoneorwithanordrinforemergencycon-traception.Methods:300healthywomenwererecruitedwithin72hoursafterunprotectedinter-courseorcontraceptivefailureandrandomlyalocatedinto3groups.Group1(n=100),mifepristone25mgtwicewith12hoursapart;group2(n=99),singledoseofmifepristone25mg;andgroup3(n=101),mifepristone25mgandanordrine7.5mggivenonce.Results:Nopregnancyoccuredingroup1,while1pregnancyineachgroup2and3.Thecontraceptiveefectivenesswere100.0%,83.8%and86.1%forthe3groupsrespectively.Theoveralmenstruationdisturbancesandsideef-fectswerelow.Conclusions:Bothmifepristone50or25mgwereefectiveforemergencycontracep-tionandnosynergeticefectsofanordrinincombinationwithmifepristonewasshowninthisstudy.
Keywords:MifepristoneNorandrostanesContraception
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