| 多次抗病毒治疗无效的慢性乙型肝炎患者停用抗病毒药物后的联合治疗 |
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| 引用本文： | 肖扬,卢成鸿,江山,潘华将,王启亮,胡侠,张文静,郑金莉,周岳进.多次抗病毒治疗无效的慢性乙型肝炎患者停用抗病毒药物后的联合治疗[J].肝脏,2011,16(1):23-26. |
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| 作者姓名： | 肖扬 卢成鸿 江山 潘华将 王启亮 胡侠 张文静 郑金莉 周岳进 |
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| 作者单位： | 1. 解放军第一一八医院肝病科,浙江温州,325000
2. 325000,浙江温州 解放军第一一八医院B超室 |
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| 摘 要： | 目的 对于干扰素治疗无效、核苷类似物耐药后停用抗病毒药物治疗的慢性乙型肝炎患者,探讨其停药的后果及再联合应用核苷类似物长期治疗的必要性.方法 先后用干扰素α-2b、核苷类似物抗病毒治疗均无效的42例慢性乙型肝炎患者,其自动停用抗病毒药物一段时间后,再联用拉米夫定(100 mg/d)(或替比夫定600 mg/d、恩替卡韦...
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| 关 键 词： | 乙型肝炎 慢性 治疗学 干扰素 核苷类似物 联合治疗 |
Combination with nucleoside/tide analogues for the patients with chronic hepatitis B who had no response to failed to interferon alpha and nucleoside/tide analogue:a 5-year clinical course |
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| XIAO Yang,LU Cheng-hong,JIANG Shan,PAN Hua-jiang,WANG Qi-liang,HU Xia,ZHANG Wen-jing,ZHENG Jin-li,ZHOU Yue-jin.Combination with nucleoside/tide analogues for the patients with chronic hepatitis B who had no response to failed to interferon alpha and nucleoside/tide analogue:a 5-year clinical course[J].Chinese Hepatology,2011,16(1):23-26. |
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| Authors: | XIAO Yang LU Cheng-hong JIANG Shan PAN Hua-jiang WANG Qi-liang HU Xia ZHANG Wen-jing ZHENG Jin-li ZHOU Yue-jin |
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| Institution: | XIAO Yang,LU Cheng-hong,JIANG Shan,PAN Hua-jiang,WANG Qi-liang,HU Xia,ZHANG Wen-jing,ZHENG Jin-li,ZHOU Yue-jin.Department of Liver Diseases,118th Hospital of P.L.A,Wenzhou 325000,China |
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| Abstract: | Objective To evaluate the clinical risk of patients with chronic hepatitis B(CHB) who stop antiviral therapy and identify the significance of sustained combination therapy with nucleoside/tide analogues.Methods Forty-two CHB patients treated with invalid interferon alpha and nucleoside/tide analogues were received two kinds of nucleoside/tide analogues(adefovir dipivoxil 10 mg/d and lamivudine 100 mg/d or telbivudine 600 mg/d or entecavir 0.5 mg/d for two years).The risk of stopping antiviral therapy and ef... |
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| Keywords: | Chronic hepatitis B Therapeutics interferon nucleoside/ tide analogue Combination therapy |
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