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The human gut microbiome and health inequities
Authors:Katherine R Amato  Marie-Claire Arrieta  Meghan B Azad  Michael T Bailey  Josiane L Broussard  Carlijn E Bruggeling  Erika C Claud  Elizabeth K Costello  Emily R Davenport  Bas E Dutilh  Holly A Swain Ewald  Paul Ewald  Erin C Hanlon  Wrenetha Julion  Ali Keshavarzian  Corinne F Maurice  Gregory E Miller  Geoffrey A Preidis  Laure Segurel  Burton Singer  Sathish Subramanian  Liping Zhao  Christopher W Kuzawa
Abstract:Individuals who are minoritized as a result of race, sexual identity, gender, or socioeconomic status experience a higher prevalence of many diseases. Understanding the biological processes that cause and maintain these socially driven health inequities is essential for addressing them. The gut microbiome is strongly shaped by host environments and affects host metabolic, immune, and neuroendocrine functions, making it an important pathway by which differences in experiences caused by social, political, and economic forces could contribute to health inequities. Nevertheless, few studies have directly integrated the gut microbiome into investigations of health inequities. Here, we argue that accounting for host–gut microbe interactions will improve understanding and management of health inequities, and that health policy must begin to consider the microbiome as an important pathway linking environments to population health.
Keywords:structural racism  health disparities  chronic disease  DOHad  policy
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