健脾消胀片对大鼠胆汁分泌的影响

目的：观察健脾消胀片对大鼠胆汁分泌的影响。方法：大鼠60只,分为6组,分别灌服健脾消胀片（大、中、小剂量）混悬液;舒胆通混悬液;清肝利胆胶囊混悬液和同体积的0.5%羧甲基纤维素;每天给药1次,连续给药5 d。收集各组大鼠胆汁量,检测胆汁中总胆汁酸、总胆固醇、总胆红素等含量。结果：健脾消胀片可使大鼠胆汁中胆汁酸、胆红素含量显著升高（P〈0.01）,胆固醇含量显著降低（P〈0.01）。结论：健脾消胀片有促进胆汁分泌的作用。

Effect of Jianpi Xiaozhang Tablets on Biliation in Rats

Objective： To observe the effect of Jianpi Xiaozhang tablets on the bile secretion in rats. Methods： Totally 60 rats were divided into 6 groups randomly. Jianpi Xiaozhang tablet suspension （ high, moderate, tow dosages）, Shudantong suspension, Qinggan Lidan capsule suspension and 0.5% carboxymethyl cellulose with the same volume was respectively given with intragastric gavage once daily for continuous 5 days. The bile was collected to detect total bile acids （TBA） , total cholesterol and total bilirubin. Re- suits： Jianpi Xiaozhang tablets could notably increase TBA and total bilirubin in the bile （P 〈 0.01 ）, and decrease the cholesterol content significantly （P 〈 0.01 ）. Conclusion ： Jianpi Xiaozhang tablets can promote the bile secretion.