| 白藜芦醇对正常家兔血流动力学的影响 |
| |
| 引用本文： | 王桂英,宋翠淼,张丽男,岳华,冯静坤,李乾,王娜.白藜芦醇对正常家兔血流动力学的影响[J].河北中医药学报,2007,22(2):6-8. |
| |
| 作者姓名： | 王桂英 宋翠淼 张丽男 岳华 冯静坤 李乾 王娜 |
| |
| 作者单位： | 河北医科大学基础课部,石家庄,050091 |
| |
| 基金项目： | 河北省中医药管理局资助项目(05054) |
| |
| 摘 要： | 目的:观察白藜芦醇(Res)对正常家兔血流动力学的影响。方法:经麻醉家兔右侧颈总动脉插管进入左心室,通过生物信号记录系统观察Res对正常家兔血流动力学的影响。结果:与空白对照组相比,Res呈剂量依赖性降低心率(HR)、左室收缩内压峰值(LVSP)、左室内压上升/下降速率最大值(lv±dp/dtmax);并可降低收缩压(SBP),而对左室舒张压峰值(LVDP)、左室舒张末期压(LVEDP)、心室内压变化时间(t-dp/dtmax)等无明显影响。结论:本实验证实白藜芦醇可以减慢心率,降低心肌收缩力。
|
| 关 键 词： | 白藜芦醇 血流动力学 家兔 |
| 文章编号： | 1007-5615（2007）02-0006-03 |
| 收稿时间： | 2007-04-08 |
| 修稿时间： | 2007年4月8日 |
Effect of Resvaratrol on Hemodynamics in Rabbits |
| |
| WANG Gui-ying SONG Cui-miao ZHANG Li-nan et al Basic Medical College,Hebei Medical University.Effect of Resvaratrol on Hemodynamics in Rabbits[J].Journal of Hebei Traditional Chinese Medicine and Pharmacology,2007,22(2):6-8. |
| |
| Authors: | WANG Gui-ying SONG Cui-miao ZHANG Li-nan Basic Medical College Hebei Medical University |
| |
| Institution: | shijiazhuang 050091 |
| |
| Abstract: | Objective: to observe the effects of Res on hemodynamics in rabbits. Methods:A tube was inserted through right common carotid artery of anesthetized rabbit into left ventricle, and the effect was observed with biological signal disposal system.Results:Compared with blank group,Res obviously decreased HR,LVSP,1v dp/dtmaxand 1v-dp/dtmax,with does dependence in certain time. Res decreased SBP,but there is no significantly changes of LVDP,LVEDP and t-dp/dtmax.Conclusion:Res can weaken cardiac muscle contraction and reduce HR. |
| |
| Keywords: | resvaratrol(Res) hemodynamics rabbit |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
