原发性肝癌TACE治疗后影响发热的因素

目的 探讨影响原发性肝癌TACE治疗后发热程度的因素。方法 将102例TACE病例17项临床数据与治疗后发热时间作多元相关回归分析，判断影响发热的因素。结果 影响TACE治疗后发热的因素有碘油用量、腹水、加用明胶海绵、白蛋白水平、术前发热史、术前白细胞计数以及年龄等。结论 碘油用量是决定TACE治疗后发热的首要因素；明胶海绵会加重发热。治疗前的全身状态和肝脏的局部状态也是影响发热的重要因素。有些发热病例可能和潜在的感染有关。通过建立多元回归方程可以对发热的时间进行大致的预测。

Analysis of the factors affecting the post-treatment fever in 102 TACE procedures for primary hepatic cancer

Objective To Investigate the factors affecting the post treatment fever in patients with primary liver cancer (PLC) undergone transcatheter arterial chemo embolization(TACE).Methods Seventeen clinical parameters of 102 TACE procedures were determined as independent variables, while the numbers of days running a fever after the procedure of the patients were determined as dependent variables. A multivariate stepwise regression analysis was performed to determine the factors that had affected the duration of fever. Results The factors that affected the fever after TACE were the dose of lipiodol used, ascites, using gelatin sponge(GS), serum albumin level, a history of fever, pre operative leukocyte counts and age. The volume of lipiodol used had played the most important role in affecting febrile time. Conclusions The amount of lipiodol used is the most important factor affecting the post treatment fever in patients with PLC undergone TACE with a tendency of intensification by using GS. The systemic state and the regional state of the liver before the treatments also play some parts in affecting the fever. Some frbrile cases are probably associated with potential infection. The lasting time of fever can be predicted approximately by building up a multivariate regresion equation.