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医用射线防护喷剂防治皮肤黏膜放射性损伤的临床观察
引用本文:张力元,常韵芳,王彬彬,朱雅群,毛卫东,田野.医用射线防护喷剂防治皮肤黏膜放射性损伤的临床观察[J].中华放射医学与防护杂志,2006,26(6):597-599.
作者姓名:张力元  常韵芳  王彬彬  朱雅群  毛卫东  田野
作者单位:215004,苏州大学附属第二医院放疗科
基金项目:装备预先研究资助项目(616010305)
摘    要:目的探讨“医用射线防护喷剂”对皮肤和黏膜急性放射性损伤的临床价值。方法70例首程放疗的头颈部恶性肿瘤患者,采用随机分组研究观察。观察组:用“医用射线防护喷剂”;对照组:不行任何治疗。结果观察组皮肤黏膜的辐射损伤耐受剂量明显高于对照组(P〈0.05);观察组中发生严重皮肤黏膜放射性损伤的概率低于对照组(P〈0.05)。结论“医用射线防护喷剂”对急性皮肤黏膜放射性损伤有明显的防护作用。

关 键 词:急性皮肤放射性损伤  急性黏膜放射性损伤  超氧化物歧化酶  医用射线防护喷剂
收稿时间:2005-12-09
修稿时间:2005年12月9日

Effect of protective spray against rays for medical use
ZHANG Li-yuan,CHANG Yun-fang,WANG Bin_bin.Effect of protective spray against rays for medical use[J].Chinese Journal of Radiological Medicine and Protection,2006,26(6):597-599.
Authors:ZHANG Li-yuan  CHANG Yun-fang  WANG Bin_bin
Institution:Department of Radiotherapy, No. 2 Hospital Affiliated to Suzhou University, Suzhou, 215004, China
Abstract:Objective To evaluate the effect of the Protective Spray against Rays for Medical Use on the acute mucocutaneous membrane injury induced by irradiation. Methods 70 patients who suffered from the malignant tumor of the head and neck were randomized into 2 groups after receiving radiotherapy for the first time. The treatment group was administered with the spray, while the control group was not. Results The radiation injury tolerance dose of mucocutaneous membrane in the treatment group was significantly higher than that in the control group (P<0.05), while the probability of the severe mucocutaneous membrane radiation injury in the treatment group is lower than that in the control group (P<0.05). Conclusions The Protective Spray against Rays for Medical Use has a protective effect on the acute mucocutaneous membrane injury induced by irradiation.;
Keywords:Acute skin injury induced by iradiation  Acute mucous membrane injury induced by iradiafion  Superoxide dismutase  Protective Spray against Rays for Medical Use
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