多形性胶质母细胞瘤的影像与病理分析

目的:通过分析多形性胶质母细胞瘤的影像与病理间对应关系,探讨其影像表现的病理基础。方法:经手术病理证实的多形性胶质母细胞瘤21例,其中20例行CT扫描,18例行MRI检查,分析其影像表现与病理间关系。结果:多形性胶质母细胞瘤CT表现为混杂密度影,瘤内常伴有囊变、坏死及出血,瘤周水肿及占位效应明显;MRI表现为长T1长T2或混杂信号团块,增强扫描呈厚薄不一的不规则环状、花瓣状强化,部分可见壁结节。结论:多形性胶质母细胞瘤的影像学表现与瘤体内的病理改变密切相关,认真分析其影像特征有助于术前明确诊断及评价预后。

Imaging Diagnosis of Glioblastoma Multiforme

Objective:To study the relationship between the imaging and pathological manifestations of glioblastoma multiforme.Methods:Of the 21 cases with glioblastoma multiforme proved by surery and pathology,20 of them had CT,while 18 cases had MRI,correlation between imaging and pathological manifestations was studied.Results:CT appearance of glioblastoma multiforme were heterogeneously attenuated due to cystic degeneration,necrosis and hemorrhage within the tumor.Marked peri-tumoral edema and mass effect could also be revealed.MRI showed mass with long T_1 and long T_2 or mixed signal intensities.After contrast administration,the lesion showed irregular ring-like or petal-like enhancement with varied thickness,sometimes intra-mural nodules could also be found.Conclusion:The imaging and pathology manifestations of glioblastoma multiforme are closely correlated,to study and analyze the CT features carefully is helpful for the pre-surgical diagnosis and prognosis prediction.