大涎腺上皮性肿瘤212例临床分析

目的 总结大涎腺上皮性肿瘤的临床特点,指导临床实践。方法 按照WHO 1991年涎腺肿瘤组织学分类标准,对212例经病理确诊的大涎腺上皮性肿瘤进行回顾性临床分析,讨论良、恶性肿瘤的不同临床特征。结果 212例肿瘤中,腺瘤166例(78.3％),以多形性腺瘤为主;涎腺癌46例(21.7％),以腺样囊性癌最多见。腮腺是最主要发病部位。涎腺腺瘤临床多表现为无痛性肿块,涎腺癌常伴有疼痛和(或)神经麻痹等症状。结论 大涎腺良、恶性肿瘤具有不同的临床特征,有助于临床正确诊断。

A Clinical Analysis of 212 Cases with Epithelial Major Salivary Gland Tumors

Objective To investigate the clinical features of epithelial major salivary gland tumors. Methods 212 cases of epithelial major salivary gland tumors were reviewed and pathologic diagnosis was based on the WHO Classification (1991).The clinical features were analyzed. Special attention was paid to the differences between benign and malignant tumors. Results Adenoma accounted for 78.3% and carcinoma for 21.7% of all tumors. The most common adenoma was pleomorphic adenoma and the most common carcinoma was adenoid cyst carcinoma. Parotid gland was the gland which was most commonly affected. Adenomas presented mainly as asymptomatic masses. Pain and nerve palsy were often present in the cases of carcinoma. Conclusion There were different clinical features between benign and malignant major salivary gland tumors, which was helpful to clinical diagnosis.