金线莲组织培养苗降血糖作用的研究

目的研究金线莲组织培养苗提取物(TCAE)对糖尿病小鼠的降血糖作用。方法观察TCAE对正常小鼠血糖的影响,并分别采用肾上腺素的四氧嘧啶制备高血糖小鼠模型。对肾上腺素所致高血糖小鼠和四氧嘧啶所致高血糖模型小鼠均灌予TCAE,TCAE大剂量组(4g/kg)、TCAE小剂量组(2g/kg),分别测定各组小鼠血糖。结果TCAE大剂量组可显著降低肾上腺素高血糖小鼠血糖的含量;TCAE小剂量组即可明显降低四氧嘧啶所致高血糖小鼠的血糖含量,而TCAE大剂量组及TCAE小剂量组对正常小鼠血糖均无显著影响。结论TCAE对四氧嘧啶致糖尿病小鼠及肾上腺素高血糖小鼠具有明显的降血糖作用。

Action of Lowering Blood Glucose of Tissue Cultured-Seedlings Extract of Anoectochilus Roxburghii on Diabetic Mice

Objective To study the action of the tissue cultured-seedlings of Anoectochilus roxburghii extract (TCAE) on blood glucose levels in diabetic mice. Method Experimental observation was performed by using various models. Diabetic mice were induced by Alloxan and Adrenalin. Mice in model group were given TCAE once a day. After that the contents of blood glucose were determined by auto-biochemistry analyzer. Results TCAE of 4 g/kg and 2-4 g/kg could significantly lower the blood glucose levels in Alloxan and Adrenalin model mice,separately,while had no hypoglycemic effect on the normal mice. Conclusion TCAE has the function of hypoglycemic effect in Alloxan diabetic mice and hyperglycemia mice induced by Adrenalin.