| 肝细胞癌血清血管内皮生长因子和细胞间粘附分子-1的测定及其临床意义 |
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| 引用本文： | 廖维甲,梅铭惠,覃理灵,徐静. 肝细胞癌血清血管内皮生长因子和细胞间粘附分子-1的测定及其临床意义[J]. 右江医学, 2006, 34(2): 126-127 |
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| 作者姓名： | 廖维甲 梅铭惠 覃理灵 徐静 |
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| 作者单位： | 1. 桂林医学院附属医院肝胆外科研究室,广西桂林,541001
2. 桂林医学院附属医院肝胆外科,广西桂林,541001 |
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| 摘 要： | 目的观察血清血管内皮生长因子(VEGF)、细胞间粘附分子-1(ICAM-1)在肝细胞癌(HCC)手术前后的变化,探讨其在肝癌诊断中的价值。方法应用酶联免疫分析法测定56例HCC手术患者VEGF及ICAM-1水平,并与60例正常对照组进行比较。结果肝癌患者血清中VEGFI、CAM-1含量明显高于正常对照组(P<0.001),HCC患者手术后血清中VEGFI、CAM-1含量明显下降(P<0.01)。结论血清ICAM-1及VEGF水平的升高与HCC病情的发展,预后判断及疗效观察关系密切。
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| 关 键 词： | 肝癌 血管内皮生长因子 细胞间粘附分子-1 酶联免疫吸附法 |
| 文章编号： | 1003-1383（2006）02-0126-02 |
| 收稿时间： | 2006-01-09 |
| 修稿时间： | 2006-03-30 |
Study on the test of Serum vascular endothelial growth factors and Intercellular Adhesion Molecule-1 and the clinical significance |
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| LIAO Wei-jia,MEI Ming-hui,QIN Li-ling,XU Jing. Study on the test of Serum vascular endothelial growth factors and Intercellular Adhesion Molecule-1 and the clinical significance[J]. Youjiang Medical Journal, 2006, 34(2): 126-127 |
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| Authors: | LIAO Wei-jia MEI Ming-hui QIN Li-ling XU Jing |
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| Affiliation: | 1. Department of Hepatobiliary lab. 2. Hepartment of Hepatobiliary Surgery,The Affiliated Hospital of Guilin Medical College, Guilin, Guangxi,China 541001 |
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| Abstract: | Objective To study the post-operative change of serum vascular endothelial growth factors(VEGF) and intercellular adhesion molecule-1(ICAM-1) in hepatocellular carcinoma(HCC) and the value in the diagnosis of liver cancer.Methods 56 patients with surgical operation of HCC and 60 healthy people were divided into treatment group and control group.Their Serum levels of VEGF and ICAM-1-were determined by ELISA,and were compared with control group.Results Level of VEGF and sICAM-1 in treatment group was higher than the control group,P<0.00l.level of VEGF and sICAM-1 dropped obviously after operation in control group.P<0.01.Conclusion The increase of serum ICAM-1 and VEGF are related with the development and prognosis and clinical effect of HCC. |
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| Keywords: | liver cancer vascular endothelial growth factors(VEGF) intercellular adhesion molecule-1(ICAM-1) enzyme linked immunosorbent assay(ELISA) |
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