| 表面抗原和抗体双阳性慢性乙型肝炎发生机制的研究进展 |
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| 引用本文： | 孙丙虎,张振华,李旭. 表面抗原和抗体双阳性慢性乙型肝炎发生机制的研究进展[J]. 国际流行病学传染病学杂志, 2012, 39(4): 280-284 |
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| 作者姓名： | 孙丙虎 张振华 李旭 |
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| 作者单位： | 安徽医科大学第一附属医院感染病科,合肥,230022 |
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| 基金项目： | 安徽高校省级自然科学研究项目基金，高等学校博士学位学科点专项科研基金 |
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| 摘 要： | 典型的慢性HBV感染血清学特征是存在HBsAg，而抗-HBs阴性，但近年来有关nSsAs和抗-HBs双阳性的慢性HBV感染的报道越来越多，其具体发生机制仍有争论，故本文就其可能的相关机制作以下综述。
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| 关 键 词： | 肝炎病毒 乙型 肝炎表面抗原 抗-HBs 双阳性 |
The mechanisms of the co-existence of HBsAg and anti-HBs in chronic hepatitis B carriers |
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| SUN Bing-hu , ZHANG Zhen-hua , LI Xu. The mechanisms of the co-existence of HBsAg and anti-HBs in chronic hepatitis B carriers[J]. International Journal of Epidemiology and Infectious Disease, 2012, 39(4): 280-284 |
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| Authors: | SUN Bing-hu ZHANG Zhen-hua LI Xu |
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| Affiliation: | .(Department of Infectious Diseases, the First Aliated Hospital, Anhui Medical University, Hefei 230022, China.) |
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| Abstract: | The typical serological feature of chronic HBV infection is the presence of circ~ating HBsAg in pa- tients and lack of anti-HBs. However, the co-existence of HBsAg and anti-HBs in patients with chronic HBV infection has been reported more and more. So far, the mechanism underlying the presence of both HBsAg and anti-HBs remains un- known. This review focuses on the possible mechanisms leading to this phenomenon. |
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| Keywords: | Hepatitis B virus Hepatitis B virus surface antigens Anti-HBs Co-existence |
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