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Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS‐active carbamate derivatives of valproic acid
Authors:Tawfeeq Shekh‐Ahmad  Hafiz Mawasi  John H. McDonough  Richard H. Finnell  Bogdan J. Wlodarczyk  Eylon Yavin  Meir Bialer
Affiliation:1. Faculty of Medicine, Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, , Jerusalem, Israel;2. Pharmacology Branch, Research Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, , Maryland, U.S.A;3. Department of Nutritional Sciences, Dell Pediatric Research Institute, The University of Texas at Austin, , Austin, Texas, U.S.A;4. David R. Bloom Center for Pharmacy, The Hebrew University of Jerusalem, , Jerusalem, Israel
Abstract:
Keywords:New antiepileptic drugs  Valproic acid  Carbamates derivatives of VPA  CNS drugs  Enantioselective pharmacokinetic  Pharmacodynamic analysis
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