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枸杞子抗抑郁研究与应用
引用本文:黄世敬. 枸杞子抗抑郁研究与应用[J]. 中医药学刊, 2014, 0(8): 1841-1843
作者姓名:黄世敬
作者单位:中国中医科学院广安门医院,北京100053
基金项目:国家自然科学基金项目(81072801); 北京市中医局项目(JJ2011-84); 北京市科技计划项目(Z141100002214014)
摘    要:旨在探讨枸杞子的抗抑郁作用及其相关应用。通过检索近年国内外有关枸杞子抗应激、抗抑郁文献,从枸杞子及活性成分、枸杞子复方制剂的抗抑郁研究进行阐述,表明枸杞子及枸杞多糖具有明确的抗抑郁作用,其机理涉及下丘脑-垂体-肾上腺轴功能、抗氧化损伤及神经保护作用等。枸杞子抗抑郁作用的深入研究对揭示抑郁症发病机制、研发抗抑郁新药具有参考价值。

关 键 词:枸杞子  抗抑郁  应用

Application and Research of Wolfberry Fruit in Treatment of Depression
HUANG Shijing. Application and Research of Wolfberry Fruit in Treatment of Depression[J]. Study Journal of Traditional Chinese Medicine, 2014, 0(8): 1841-1843
Authors:HUANG Shijing
Affiliation:HUANG Shijing ( Guang' anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China)
Abstract:It was to explore antidepressive effects of wolfberry fruit and its related application by retrieving the literature both at home and abroad in recent years about anti - stress, antidepressive effects of wolfberry fruit. Its antidepressant studies of wolfberry fruit,its active ingredients, and compound preparations were expounded. The results showed that anti- depressive effects of wolfberry fruit and lycium barbarum polysaccharide were clear and their mechanism was related to the hypothalamus - pituitary - adrenal axis function, anti oxidative damage and nerve protection, etc. In - depth study of wolfberry fruit antidepressant effects to reveal the pathogenesis of depression, research and development of antidepressantdrugs would have reference value.
Keywords:wolfberry fruit  anti - depression  application compatibility
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