丹红针对缺血性脑卒中患者血脂水平及神经功能缺损评分的影响

目的：观察中药丹红注射液对缺血性脑卒中的临床疗效。方法：将符合标准的160例患者随机分为观察组和对照组。两组患者均采取西医常规处理。对照组使用银杏叶提取物注射液治疗,观察组使用丹红注射液治疗。两组患者均连续治疗21d。观察患者治疗后NFDS评分、NIHSS评分、Barthel指数、血脂改变情况以及不良反应发生情况。结果：观察组临床痊愈率和总有效率分别为31.25%、95.00%,对照组分别为28.75%、9375%。组间比较,差异均无统计学意义（P〉0.05）。观察组和对照组的愈显率分别为78.75%、65.00%,差异有统计学意义（P〈0.05）。治疗后第21天观察组患者的NFDS评分和NIHSS评分均低于对照组,Barthel指数均高于对照组。组间比较,差异均有统计学意义（P〈0.05）。两组患者治疗后TC、TG和LDL-C均降低,HDL-C均升高。组间比较,TG、LDL-C和HDL-C差异均有统计学意义（P〈0.05）。两组患者在治疗过程中均未见明显不良反应。结论：丹红注射液能协助改善缺血性脑卒中患者的神经功能和日常生活活动能力,降低血脂含量,临床疗效优于银杏叶提取物注射液。

For Danhong Affect Lipid Levels in Patients with Ischemic Stroke and Neurological Deficit Scores

Objective ： to study the effects of danhong injection on cerebral ischemic stroke ： clinical efficacy. Methods ： standard 160 patients were randomly assigned to observation group and the control group. 2 groups were treated with Western medicine. Control group treatment with Ginkgo biloba extract injection, observation group of danhong injection therapy. 2 groups of patients are treated by continuous 21d. NFDS scores after treatment in patients with observation, NIHSS score, Barthel index and blood lipid changes and incidence of adverse reactions. Results ： to observe the clinical cure rate and to- tal effective rate were 31.25% ,95% , control 28.75% ,93.75%, respectively. Comparison between groups, the difference was not statistically significant （ P 〉 0. 05 ）. Observer Group and control group, respectively 78.75 % ,65 %, a statistically significant difference （P 〈 0.05）. 21d observation of patients after treatment the NFDS assessment and NIHSS score is lower than the control group, and Barthel index was higher than the control group. Comparison between groups, the differ- ences were statistically significant （ P 〈 0.05 ）. 2 groups after treatment in patients with TC, TG and LDL - C were re- duced, HDL - C rise. Comparison between groups, TG, LDL - C and HDL - C differences are statistically significant （ P 〈 0. 05 ）. 2 Group during the course of treatment in patients with no significant adverse effects. Conclusion ： danhong injec- tion of Salvia mihiorrhiza can assist in improving neurological function of patients with ischemic stroke and ADL,lower lipid content, efficacy superior to Ginkgo biloba extract injection.