电针神门、太渊对正常人事件相关电位P300影响的比较

目的:比较电针神门、太渊穴对大脑信息加工过程影响的差异,探讨穴位功能的相对特异性。方法:60名成年学生,随机分为电针神门组与电针太渊组,每组30人。电针频率2Hz,强度1mA,时间15min。以P 300幅度、潜伏期及脑地形图电压分布为观察指标。结果:电针神门、太渊两穴均可显著降低被试者P 300波幅(P<0.01,P<0.05);电针对P 300潜伏期无显著性影响,但电针神门穴有前移P 300潜伏期的趋势;电针两穴对脑地形图电压强度分布有不同影响,电针神门穴后高电位反应主要集中在枕叶,少量散布于左侧顶叶及右侧颞部,而电针太渊穴后高电位反应主要散见于顶叶及左侧枕叶。结论:不同经穴刺激对大脑皮层信息处理加工的影响不同,提示经穴功能存在相对差异性。

Comparative Study on Effects of Electroacupuncture Stimulation of Shenmen (HT 7) and Taiyuan (LU 9) on P 300 of Event-related Potentials and Brain Electrical Activity Mapping in Healthy Young Adults

Objective To observe the effect difference of electroacupuncture(EA) stimulation of Shenmen(HT 7) and Taiyuan(LU 9) on P 300 of event-related potentials(ERPs) in volunteer subjects,so as to explore functional specificity of acupoints in processing cerebral information.Methods Sixty healthy volunteer college students were randomly and equally divided into Shenmen(HT 7)group and Taiyuan(LU 9) group(30 persons/group).EA(2 Hz,1 mA) was applied to bilateral Shenmen(HT 7) and Taiyuan(LU 9) for 15 min.The ERPs were acquired by averaging EEG activity following Oddba Ⅱ auditory tone-double stimuli and brain electrical activity mapping(BEAM) acquired by means of Scan 4.5 collection and analysis system.Data were calculated and analyzed with SPSS 17.0 for Windows.After testing,the subjects were inquired about the perception for acupuncture stimulation and other sensations or psychological activities.Results Following EA stimulation of both HT 7 and LU 9,the amplitude of P 300 in the ERPs were significantly decreased in comparison with pre-EA stimulation in the same one group(P<0.01,P<0.05).No significant changes were found in the latencies of P 300 after EA stimulation of both HT 7 and LU 9(P>0.05).But,EA of HT 7 had a slightly stronger effect in shortening P 300 latency.With regard to the potential intensity distribution of BEAM,there were some differences between HT 7 and LU 9 groups.The high potential responses for HT 7 were found mainly in the occipital lobe,and in the left parietal lobe and the right temporal lobe,whereas those for LU 9 were found to mainly disperse in the left occipital lobe and the parietal lobe.Conclusion EA stimulation of HT 7 and LU 9 has a slight difference on lowering P 300 amplitude of ERPs,and may result in different distribution of the high potential responses in different lobes of the cerebral cortex in healthy subjects.The functional specificity of EA stimulation of different acupoints needs further study.