| Relationship between nucleus tractus solitarii and effect of guanabenz on plasma renin activity in rats |
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| 引用本文： | 张永胜,张家新,余传林,刘菊芳. Relationship between nucleus tractus solitarii and effect of guanabenz on plasma renin activity in rats[J]. 中国人民解放军军医大学学报, 1992, 0(1) |
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| 作者姓名： | 张永胜 张家新 余传林 刘菊芳 |
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| 作者单位： | Department of Pharmacology First Military Medical University，Guangzhou 510515，Department of Pharmacology，First Military Medical University，Guangzhou 510515，Department of Pharmacology，First Military Medical University，Guangzhou 510515，Department of Pharmacology，First Military Medical University，Guangzhou 510515 |
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| 摘 要： | Microinjection of 0.5μg guanabenz(GB)into the nucleus tractus solitarii(NTS)orintravenous(i.v.)injection of 10μg/kg of GB significantly lowered plasma renin activity(PRA).blood pressure(BP)and heart rate(HR)in rats i.v.10 μg/kg GB,after the bilateral NIS were de-stroyed by electric current(1 mA 20s),did not decrease PRA,BP and HR.These findings suggestthat the inhibitory action of GB on PRA,BP and HR is related to the activation of alpha-2adrenoceptors in the NTS.
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Relationship between nucleus tractus solitarii and effect of guanabenz on plasma renin activity in rats |
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| Zhang Yongsheng Zhang Jiaxin Yu Chuanlin Liu Jufang. Relationship between nucleus tractus solitarii and effect of guanabenz on plasma renin activity in rats[J]. Journal of Medical Colleges of PLA(China), 1992, 0(1) |
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| Authors: | Zhang Yongsheng Zhang Jiaxin Yu Chuanlin Liu Jufang |
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| Affiliation: | Zhang Yongsheng Zhang Jiaxin Yu Chuanlin Liu Jufang Department of Pharmacology,First Military Medical University,Guangzhou 510515 |
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| Abstract: | |
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| Keywords: | guanabenz hypothalamus renin blood pressure heart rate rats |
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